Gene stable ID Comment link gt2_baseMean gt2_log2FoldChange gt2_lfcSE gt2_stat gt2_pvalue gt2_padj Gene start (bp) Gene end (bp) Chromosome/scaffold name Gene name Gene description 6-8vs12-16_baseMean 6-8vs12-16_log2FoldChange 6-8vs12-16_lfcSE 6-8vs12-16_stat 6-8vs12-16_pvalue 6-8vs12-16_padj 1-5vs12-16_baseMean 1-5vs12-16_log2FoldChange 1-5vs12-16_lfcSE 1-5vs12-16_stat 1-5vs12-16_pvalue 1-5vs12-16_padj _merge ENSG00000116729 4964.69683029556 1.02977167019378 0.17304275577929698 5.950966658824941 2.66563388698613e-09 1.2755908883447902e-06 68098473 68233120 1 WLS Wnt ligand secretion mediator [Source:HGNC Symbol;Acc:HGNC:30238] 6210.75812552508 1.32214495961732 0.188469034147155 7.015184035935558 2.29646474622247e-12 1.2598022853652096e-09 7002.08872870912 0.4146474619005671 0.18680361905696602 2.21969715572866 0.0264393320576976 0.0944229259261173 both ENSG00000106484 9386.40216466912 1.02986099000068 0.22447009870840198 4.587965149596711 4.47587333496104e-06 0.000628199503572811 130486171 130506465 7 MEST mesoderm specific transcript [Source:HGNC Symbol;Acc:HGNC:7028] 10309.290726854 1.05996664481304 0.20697500919524398 5.12123008924788 3.03548989701187e-07 6.19616433861369e-05 10848.9205515841 0.512612801118593 0.20130838098169399 2.54640566189446 0.0108838625454137 0.0474518058948426 both ENSG00000143816 136.128898259306 1.61673524365006 0.272784873988213 5.9267774639143385 3.08937182138125e-09 1.44756378405595e-06 227918656 227947932 1 WNT9A Wnt family member 9A [Source:HGNC Symbol;Acc:HGNC:12778] 152.895427033675 1.5881651370750702 0.29101697591487197 5.45729379560192 4.8344607388875305e-08 1.16789926767327e-05 171.45945058443598 0.580797700679744 0.242782224603979 2.3922579242657798 0.0167450702553808 0.0663696799658375 both ENSG00000149131 4309.63208566147 0.524371744914104 0.179476516394227 2.9216732943618196 0.00348156531889895 0.0852219707096235 57597387 57619171 11 SERPING1 serpin family G member 1 [Source:HGNC Symbol;Acc:HGNC:1228] 4537.221013656839 0.559279874888043 0.11242010638293401 4.9749096748136905 6.52780709365512e-07 0.000122778725992948 4303.29605263385 0.598945982800464 0.20800689514358398 2.8794525411622502 0.0039836625022768605 0.0214021982572181 both ENSG00000179921 Receptor for bile acid, Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production, 81.9750445571878 1.88533301701451 0.48411755757200503 3.8943702568236 9.845417042810341e-05 0.0066496478891846 218259496 218263861 2 GPBAR1 G protein-coupled bile acid receptor 1 [Source:HGNC Symbol;Acc:HGNC:19680] 70.1434776200605 1.3803668563854299 0.34534750008020604 3.99703734952429 6.41401841467106e-05 0.005823928720521321 75.5767207695477 0.608614893089159 0.24481803685560602 2.48598878132546 0.0129192038233359 0.054160999818345004 both ENSG00000154342 826.79627123715 1.58994822647709 0.2643468127762469 6.0146298333579 1.8029821440675897e-09 9.12260201294045e-07 228006998 228061271 1 WNT3A Wnt family member 3A [Source:HGNC Symbol;Acc:HGNC:15983] 735.107868194068 1.14797932941221 0.24448559141134504 4.69548869029565 2.65970084659985e-06 0.000404827992443163 750.1671296914841 0.7188490605685809 0.27376022867497 2.62583452697965 0.00864368262745494 0.0396499203094263 both ENSG00000073150 The protein encoded by this gene belongs to the innexin family, Innexin family members are the structural components of gap junctions, This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations, https://www,ncbi,nlm,nih,gov/pmc/articles/PMC2915733/ 428.45162687385596 -0.921722943101437 0.19947711179170105 -4.62069525081116 3.8245621654201695e-06 0.000565909392516217 50170731 50180295 22 PANX2 pannexin 2 [Source:HGNC Symbol;Acc:HGNC:8600] 428.157743623518 -0.7391011880406501 0.18846167298404198 -3.92175860660662 8.79050350360751e-05 0.007418959559519 274.080561115201 0.7816408127911 0.222235187235849 3.5171784563601802 0.000436160436812921 0.00340839101442762 both ENSG00000134463 113.787416255601 -2.23917559125813 0.346346321889247 -6.46513460585894 1.01208676997909e-10 7.58761451453326e-08 11742366 11764070 10 ECHDC3 enoyl-CoA hydratase domain containing 3 [Source:HGNC Symbol;Acc:HGNC:23489] 345.46268847105006 1.28122563513853 0.19694986949308604 6.505338837929549 7.75184507334183e-11 3.45968787239385e-08 343.71568689951897 0.8505200064992121 0.16789356320806198 5.065828553803491 4.0662777181722093e-07 7.86007290883804e-06 both ENSG00000146242 7569.142249478009 1.33532472179604 0.251827778073593 5.30253148405975 1.14207761842399e-07 2.8540519684415602e-05 82363206 82367420 6 TPBG trophoblast glycoprotein [Source:HGNC Symbol;Acc:HGNC:12004] 7819.992559242759 1.17008984022728 0.156305108700994 7.485934720570261 7.103970150627128e-14 5.05572275692739e-11 7555.391111452371 0.951870079388683 0.218640371619589 4.353587913968759 1.33927351267989e-05 0.000172660959950136 both ENSG00000182168 Netrins are secreted proteins that direct axon extension and cell migration during neural development, They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors, 707.427591432924 0.754872055177203 0.237415739511293 3.1795366926011903 0.00147510692568155 0.0476831041224283 95162504 95549206 4 UNC5C unc-5 netrin receptor C [Source:HGNC Symbol;Acc:HGNC:12569] 921.314460916115 1.15695955497108 0.284723521716721 4.06344915936438 4.8352857806611496e-05 0.0045799548624593294 930.069778918009 1.0061008262981899 0.26482367068814 3.79913481179329 0.00014520209721306698 0.00135534004865962 both ENSG00000143032 Potential regulator of neural basic helix-loop-helix genes https://www,ncbi,nlm,nih,gov/pmc/articles/PMC5124293/ 220.857246672561 1.6533721925890703 0.5432796095982629 3.04331722262074 0.0023398553383663897 0.0652924149071942 90711539 90717302 1 BARHL2 BarH like homeobox 2 [Source:HGNC Symbol;Acc:HGNC:954] 323.284952272383 2.06630672639634 0.55299728521074 3.73655853592282 0.00018655603517438898 0.0132767392384109 340.459211826394 1.0256930106845699 0.457127945000716 2.24377665356459 0.024846775261922 0.0900028082416882 both ENSG00000173406 The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function, In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer, This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain, [provided by RefSeq, Jan 2017] 655.9289904005001 -1.25082515848402 0.21634507102561198 -5.781620780886401 7.398433419494921e-09 2.86893389720449e-06 56994778 58546734 1 DAB1 DAB adaptor protein 1 [Source:HGNC Symbol;Acc:HGNC:2661] 760.144191897357 -0.503959835156404 0.140621449033409 -3.583804879131 0.000338625087581408 0.0209311638643043 480.888505347061 1.02653403387909 0.17887426755663 5.7388580699797584 9.53170569687027e-09 2.69631085437288e-07 both ENSG00000006377 278.332235854525 -3.56082374814924 0.8125908013683342 -4.38206258568656 1.17561025286312e-05 0.00134901276516042 97005553 97011040 7 DLX6 distal-less homeobox 6 [Source:HGNC Symbol;Acc:HGNC:2919] 225.144008128038 -3.39236097425632 0.6349179019412281 -5.3429915330538895 9.14250354774214e-08 2.04017291033175e-05 34.8924648671571 1.24657578858634 0.4498337038864829 2.7711925047326296 0.00558513964509772 0.0279629822017576 both ENSG00000112175 387.748224899163 2.0076395368894397 0.376138779452758 5.33749681383649 9.423855836724447e-08 2.46455746074151e-05 55753653 55875590 6 BMP5 bone morphogenetic protein 5 [Source:HGNC Symbol;Acc:HGNC:1072] 519.193433764313 2.2373036426527997 0.440518649300776 5.07879438521847 3.7983751860745e-07 7.40880114071954e-05 525.352252848101 1.2690175525768799 0.35896566907162003 3.53520590383726 0.000407457525408798 0.0032210081059984 both ENSG00000168702 lipoprotein Alzgeimer disease https://www,ncbi,nlm,nih,gov/pmc/articles/PMC3537064/ 217.481683556287 1.82749860043925 0.409930799855087 4.45806609575391 8.27024034901735e-06 0.0010054377064310802 140231423 142131016 2 LRP1B LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693] 177.19763674949402 1.30820428896522 0.35155034514793204 3.7212430794648497 0.00019824449450436598 0.0139204640781039 184.704225056678 1.29759603494945 0.299945750337448 4.32610241515212 1.5177087864457901e-05 0.000193256636644201 both ENSG00000231764 functions as a Dlx-2 transcriptional coactivator https://www,ncbi,nlm,nih,gov/pmc/articles/PMC1475760/ 1742.29728192341 -5.3699041124488405 1.4413028085716701 -3.72572930581493 0.000194751316612317 0.0107724503074045 96955141 97014088 7 DLX6-AS1 DLX6 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:37151] 1427.1972783116598 -4.803066240900151 1.2444082005886998 -3.85971921321952 0.000113517385279649 0.008869851006479891 72.7544603970837 1.32102127209265 0.602511603041542 2.19252420272737 0.0283416774580353 0.0994096017468793 both ENSG00000177283 Receptor for Wnt proteins, 1508.3655399153301 -2.2907682258945496 0.494036103967048 -4.6368437600004695 3.5376961401358704e-06 0.000534002173743596 35638247 35642296 10 FZD8 frizzled class receptor 8 [Source:HGNC Symbol;Acc:HGNC:4046] 1332.79394069821 -2.06660832223602 0.459492486584258 -4.49758893251689 6.87284157578538e-06 0.0009328642493483539 425.27353674474404 1.3558242710309698 0.344367081069354 3.93714830935862 8.245564969379069e-05 0.000831765128047653 both ENSG00000167178 Required for axon extension during neural development 1929.46860008018 -1.6728719468281499 0.5054888843609979 -3.3094139131128 0.0009349151161158359 0.0348660631649851 74100311 74138540 15 ISLR2 immunoglobulin superfamily containing leucine rich repeat 2 [Source:HGNC Symbol;Acc:HGNC:29286] 1910.8985978984301 -1.11749011349455 0.331944927574216 -3.36649251326397 0.0007613064872053193 0.0386256694047986 928.343198603797 1.4216363511862498 0.371685504234597 3.8248366831356297 0.000130858804014879 0.00124115210889863 both ENSG00000133816 SRF signalling way, microtubles and mechanics of assymrtric division, Somehow linked to NOTCH https://www,researchgate,net/figure/Classical-Model-for-the-Establishment-of-Asymmetric-Stem-Cell-Division-during_fig2_301934617 148.715163975769 2.08206913970153 0.644060690435753 3.23272196334923 0.0012261683829119 0.0419878799361853 12094008 12359144 11 MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24693] 182.70551207615898 2.11573798042582 0.711388773759691 2.97409526051999 0.00293853833192975 0.0945748441622388 156.92782773871 1.48600231688379 0.545276198492054 2.72522864741445 0.0064256970970707795 0.031316008911688 both ENSG00000170458 35.3644232345936 2.8241198583094196 0.8555426328245419 3.30096917436562 0.0009635146797075119 0.0354671172852727 140631728 140633701 5 CD14 CD14 molecule [Source:HGNC Symbol;Acc:HGNC:1628] 29.8368757254191 2.26040870264904 0.5107659339884071 4.42552753077762 9.620688543687487e-06 0.00122382594556705 28.944702101588696 1.52139553080687 0.457467573998113 3.3256904254663997 0.000881998294018047 0.00609395412725505 both ENSG00000164932 linked to WNT way,look at Chip seq https://www,signalingpathways,org/ominer/query,jsf?geneSearchType=gene&findMax=y&gene=CTHRC1&species=all&reportsBy=pathways&omicsCategory=cistromics&countMax=3000 109.585803503172 2.0103459915632 0.622856121624066 3.2276250032211697 0.00124822489918616 0.0423436292723921 103371538 103382989 8 CTHRC1 collagen triple helix repeat containing 1 [Source:HGNC Symbol;Acc:HGNC:18831] 86.46418148825171 1.5264715228442498 0.505030533270011 3.022533138661009 0.0025066863527911398 0.0844067327898929 72.9466291893497 1.5814135430995802 0.427362426205157 3.70040379343134 0.00021525667613269398 0.0018937537489679892 both ENSG00000166106 Metallopeptidase 301.42477272351897 1.2988437949513 0.3396661674636761 3.82388332829821 0.00013136609607201002 0.008139269605387259 130448645 130476645 11 ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif 15 [Source:HGNC Symbol;Acc:HGNC:16305] 304.87826782802995 1.11477252438217 0.296333299731733 3.7618874604756303 0.00016863592824623998 0.0124384349091876 255.731754954706 1.6094062124113 0.350889403286525 4.58664809292379 4.50418939366064e-06 6.59793368212007e-05 both ENSG00000137672 receptor-activated calcium channel in the cell membrane, 43.548875121951 -2.57425121592949 0.7050417817367489 -3.65120377630425 0.000261014033823207 0.0131920598532983 101451564 101872562 11 TRPC6 transient receptor potential cation channel subfamily C member 6 [Source:HGNC Symbol;Acc:HGNC:12338] 41.15539030149471 -1.74287604978479 0.576910691132562 -3.0210500109874303 0.0025189975065559303 0.0847090066570094 16.7830140308694 1.62931545419716 0.582223942598341 2.798434305064609 0.00513510142612755 0.0261151115076838 both ENSG00000124749 241.257336675486 2.43496741596292 0.6118895267873199 3.97942326084177 6.90826541259314e-05 0.005094222865397779 56056590 56394094 6 COL21A1 collagen type XXI alpha 1 chain [Source:HGNC Symbol;Acc:HGNC:17025] 187.66817154753798 1.74511798759725 0.548470664817652 3.1817891084064502 0.00146368355928429 0.060315673682432 171.232985627988 1.6606579220590099 0.46329947243567204 3.5844157415689395 0.000337833601302621 0.00275632527578968 both ENSG00000104369 component of junctional complexes, вохможно как-то через SMAD 187.081518338101 -2.5571106962551298 0.530314326871993 -4.8218774539583 1.42213309023143e-06 0.0002498843385343371 74234700 74321540 8 JPH1 junctophilin 1 [Source:HGNC Symbol;Acc:HGNC:14201] 189.29222653298302 -1.38990888888153 0.452361586289234 -3.07256170950122 0.00212229947361977 0.0757835495231981 75.2800517585994 1.67835491334636 0.28313939553448697 5.927662980907693 3.07276319560065e-09 9.632486506585105e-08 both ENSG00000123700 Probably participates in establishing action potential waveform and excitability of neuronal 85.8563413531697 1.13052628174391 0.3620017067871811 3.12298605378824 0.0017902623076053899 0.0539019940566973 70168673 70180044 17 KCNJ2 potassium inwardly rectifying channel subfamily J member 2 [Source:HGNC Symbol;Acc:HGNC:6263] 101.338042499948 1.2143122906833899 0.36588087880592296 3.31887333015701 0.000903814179542275 0.0435883424463502 83.0980745861204 1.7201890475565902 0.44324669943195594 3.8808840534201403 0.000104077453240722 0.00101505968700314 both ENSG00000187889 Adapter protein that plays a role in T-cell receptor (TCR)-mediated activation of signaling pathways, Required for T-cell activation and integrin-mediated T-cell adhesion in response to TCR stimulation 98.5113040571627 2.07400469051441 0.583197964256838 3.55626188297363 0.00037616911263819 0.0175163965058914 56718789 56819696 1 FYB2 FYN binding protein 2 [Source:HGNC Symbol;Acc:HGNC:27295] 89.35730160315991 1.7092174190404998 0.48721814653006895 3.50811526872187 0.000451293464773363 0.0261750209568551 78.59619599735359 1.74576036239757 0.39569307096263595 4.411905313758741 1.02464924586096e-05 0.000136498567388227 both ENSG00000175084 Plays an important role in the loading of the cohesin complex on to DNA, 628.075077242377 3.3201387534375297 0.6973862546461429 4.76083193684708 1.92796551559801e-06 0.000319856578280629 219418377 219426735 2 DES desmin [Source:HGNC Symbol;Acc:HGNC:2770] 376.891713650289 2.23310765562929 0.5273841639799001 4.23430927234743 2.2925526015509e-05 0.00257980748307856 351.263685466787 1.75883490289951 0.5168501995077371 3.4029877604278203 0.000666532663433801 0.0048369569189680795 both ENSG00000104879 32.0167759402121 3.0251208116253197 0.6288605773944941 4.81047933416187 1.50568771451269e-06 0.000262514902225619 45306413 45322875 19 CKM creatine kinase, M-type [Source:HGNC Symbol;Acc:HGNC:1994] 69.5310204336153 3.9164952250456295 0.656961019827238 5.9615336478799925 2.49881447850754e-09 7.83318843429293e-07 68.720614490259 1.8642135602494896 0.434558276544111 4.28990462470287 1.78749865940515e-05 0.000222141506968329 both ENSG00000188707 45.3339275200778 -3.147840264306569 0.514382767571066 -6.1196456467054405 9.37836760152047e-10 5.55075962436307e-07 150322639 150332721 7 ZBED6CL ZBED6 C-terminal like [Source:HGNC Symbol;Acc:HGNC:21720] 176.235251510924 1.72587719301244 0.28861800396474896 5.979797411471361 2.23415301056284e-09 7.08791771977598e-07 142.766663104661 1.9701940264915705 0.423021618199016 4.65743106671363 3.20179579318714e-06 4.88575146468028e-05 both ENSG00000237125 neuroblastoma transcript 301 162.11862668382298 2.20374403420379 0.591446130054494 3.72602663576604 0.00019452185789878705 0.0107724503074045 173527270 173659696 4 HAND2-AS1 HAND2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:48872] 181.261134406284 2.0106612379492597 0.5920754948561889 3.39595415688945 0.000683898128293121 0.0357013789762388 155.430309366672 2.00440157949388 0.469737999473104 4.26706287705524 1.98063349575098e-05 0.00024252655050012003 both ENSG00000144355 SMAD, This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene, The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members, https://www,cell,com/fulltext/S0896-6273(07)00493-X 1286.84855937065 -4.33107488192365 1.35013140206835 -3.2078913765642403 0.00133711990169234 0.0445528351243889 172084740 172089677 2 DLX1 distal-less homeobox 1 [Source:HGNC Symbol;Acc:HGNC:2914] 996.6510599617053 -4.13405346943622 1.00105131500052 -4.1297118414295095 3.6321819232874105e-05 0.00365048146580169 86.5087737117556 2.1088368912382003 0.41219682016515 5.11609209016526 3.11930808818529e-07 6.2096378663277295e-06 both ENSG00000061455 Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation, 117.617204917225 1.83949355198867 0.64337383381747 2.85913640763723 0.00424796076380852 0.0966035243061855 123089241 123194266 5 PRDM6 PR/SET domain 6 [Source:HGNC Symbol;Acc:HGNC:9350] 117.324038223196 2.0010686175700103 0.569589394452755 3.5131774521409 0.000442781651631893 0.0259673194894677 120.06300927282 2.1123837283777 0.4962767951573821 4.25646282274352 2.07686552932064e-05 0.000252353041229725 both ENSG00000134762 Component of intercellular desmosome junctions, Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion, May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms 328.317832943278 1.98632795007234 0.660337994517558 3.0080473432753903 0.00262932173699017 0.0708216469301149 30989365 31042815 18 DSC3 desmocollin 3 [Source:HGNC Symbol;Acc:HGNC:3037] 282.347198805932 1.47071770095489 0.430848024864445 3.41354170398625 0.000641243435261968 0.034111559873369994 228.60196913453998 2.13249933284471 0.34856960534647596 6.11785795472619 9.4841546419753e-10 3.35524338749126e-08 both ENSG00000115844 Acts as a transcriptional activator, Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina, Likely to play a regulatory role in the development of the ventral forebrain, May play a role in craniofacial patterning and morphogenesis 1592.26658671493 -4.55245181564389 1.2656045770497 -3.59705700990452 0.000321837964550465 0.0155331709457178 172099438 172102900 2 DLX2 distal-less homeobox 2 [Source:HGNC Symbol;Acc:HGNC:2915] 1273.6557653492998 -4.149050520339681 0.955661765206977 -4.341547052937799 1.4148297081220099e-05 0.00169192630358567 106.672353641 2.1869609906826497 0.34185043990960196 6.3974204370219825 1.58023772707239e-10 6.57519165217363e-09 both ENSG00000176435 cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response, This family member plays a role in cell-cell adhesion and angiogenesis, It functions in filopodia formation, cell migration and tube formation, 79.30144171512991 2.7128878538208996 0.7112940353904209 3.81401743701087 0.000136725814761026 0.00837901989043661 38254000 38256093 14 CLEC14A C-type lectin domain containing 14A [Source:HGNC Symbol;Acc:HGNC:19832] 54.92192033206661 1.82342744772992 0.5291294043256429 3.44608980869965 0.000568761305231218 0.0312664356771366 45.6478324637039 2.2818580461072098 0.41908534246582 5.4448529091501605 5.1848212152462195e-08 1.2503588139661301e-06 both ENSG00000164946 674.787859621733 1.85269712862393 0.5532487270822329 3.348759857785529 0.0008117411961048057 0.0315862824249017 14737152 14910995 9 FREM1 FRAS1 related extracellular matrix 1 [Source:HGNC Symbol;Acc:HGNC:23399] 935.18919147495 2.2636975977361296 0.695755099288294 3.253583911999669 0.00113959062973787 0.0511204437176451 781.340327281913 2.40787315534245 0.505927045569971 4.759328793402951 1.94237803523138e-06 3.17728140986595e-05 both ENSG00000145244 linked to WNT 33.6660729560045 1.97841608987214 0.6924408520579239 2.8571625778466405 0.00427446836529311 0.0969123669393218 47593999 47838106 4 CORIN corin, serine peptidase [Source:HGNC Symbol;Acc:HGNC:19012] 102.909908232382 3.3596538562590403 0.755720179278505 4.44563205850418 8.76338275086786e-06 0.00113673593396972 83.4190163453184 2.46881004551084 0.5942403576273211 4.15456475451834 3.25907313897841e-05 0.000371051970282172 both ENSG00000104332 WNT 9402.68672687755 -2.06189040437105 0.3745355575003521 -5.505192666170571 3.68764751505353e-08 1.0913010560667e-05 41261962 41309473 8 SFRP1 secreted frizzled related protein 1 [Source:HGNC Symbol;Acc:HGNC:10776] 11256.759944880801 -0.7909922655229141 0.247042421162394 -3.20184793284127 0.00136549061199563 0.0579003201208838 5260.72341535182 2.51895188532262 0.247006990949323 10.1978971349819 2.02611787223668e-24 6.986613352540269e-22 both ENSG00000015413 dipeptidase 81.394965521027 1.96867822602756 0.664523084628851 2.96254302004738 0.00305109170069484 0.0779796630003723 89613308 89638456 16 DPEP1 dipeptidase 1 [Source:HGNC Symbol;Acc:HGNC:3002] 77.5376694264868 1.85125408908133 0.502109534682471 3.68695266910645 0.000226955548950998 0.0157268250394149 53.640196714875096 2.5252475723132997 0.48523384828511 5.204186767345081 1.94847971317628e-07 4.09918593234841e-06 both ENSG00000127399 245.082984821011 -3.30964541800265 0.491270473962417 -6.7369109144870905 1.61789304616201e-11 1.45552130004919e-08 150323263 150338156 7 LRRC61 leucine rich repeat containing 61 [Source:HGNC Symbol;Acc:HGNC:21704] 795.666901799621 1.1558087716593999 0.33619556195461997 3.4379060953083505 0.000586230958081004 0.0318281104911113 593.1729500841079 2.5707122102703597 0.356318297671498 7.2146511337466706 5.407242241714188e-13 3.58887759405809e-11 both ENSG00000105880 homeobox transcription factor 588.240518470198 -3.65160038564304 1.1655929700673702 -3.1328263634191003 0.00173131830306298 0.0525493656601749 97020396 97024950 7 DLX5 distal-less homeobox 5 [Source:HGNC Symbol;Acc:HGNC:2918] 495.893190904544 -2.85493348967369 0.698603887459573 -4.08662697262603 4.376899940702221e-05 0.0042062966875390795 83.99844786902841 2.6839909322895603 0.4866681634146339 5.515032899332759 3.4871472004701695e-08 8.805927273914579e-07 both ENSG00000080293 Secretin Receptor https://www,researchgate,net/figure/Relationships-between-TLX-and-its-upstream-downstream-and-interacting-molecules-are_fig1_289535333 56.090917555129 2.0940558493345702 0.601625604491505 3.48066278047536 0.000500174789025573 0.0215471295500427 119439843 119525301 2 SCTR secretin receptor [Source:HGNC Symbol;Acc:HGNC:10608] 57.0364402627878 1.75815968749822 0.5735287071671971 3.06551296478638 0.00217296956450579 0.0772181303273503 43.87485248641789 2.8190730810778906 0.6145412907473361 4.587280177137731 4.49057854858356e-06 6.58982082871876e-05 both ENSG00000205835 Regulator of DNA replication, Promotes initiation of chromosomal DNA replication by mediating TOPBP1- and CDK2-dependent recruitment of CDC45L onto replication origins (By similarity), 101.55759774859699 2.4366996266247596 0.523847558874473 4.65154334566375 3.29460004727612e-06 0.000507526367556762 190852737 190892429 3 GMNC geminin coiled-coil domain containing [Source:HGNC Symbol;Acc:HGNC:40049] 108.806509006194 2.16586033133574 0.5035547605789861 4.30114160542428 1.69920425812655e-05 0.00196243186513107 85.5207034464274 3.2261493513847 0.481510236259966 6.70006389987296 2.08328421073811e-11 1.0129420797754198e-09 both ENSG00000277632 This locus represents a small inducible cytokine, 12.7637549477371 4.18277101314746 1.14421971833065 3.65556627467483 0.000256614900457738 0.0130873599233446 36088256 36090169 17 CCL3 C-C motif chemokine ligand 3 [Source:HGNC Symbol;Acc:HGNC:10627] 10.2178538329749 3.52738014672775 1.00459844371108 3.5112339351206803 0.000446031702090655 0.0260997928432247 9.69016882894683 3.30318658566141 0.7730705790421751 4.27281373164403 1.93021693209541e-05 0.000237419056838304 both ENSG00000101336 tyrosine-protein kinase, regulation of cytoskelet folding 79.85332219197791 2.8069090365388703 0.740852866195947 3.7887536980878402 0.00015140492776916298 0.00905879637661997 32052197 32101856 20 HCK HCK proto-oncogene, Src family tyrosine kinase [Source:HGNC Symbol;Acc:HGNC:4840] 48.81468233493871 1.7353308807243202 0.516480201642782 3.35991752482419 0.000779657436744696 0.0393293862535658 37.173120203058794 3.39581984237086 0.507460160816819 6.691795937054192 2.2044814059637398e-11 1.06668455127278e-09 both ENSG00000148704 110.62804816985 -2.42960295630459 0.621246323262064 -3.91085285390043 9.19707926925855e-05 0.00626822757105739 117128521 117138301 10 VAX1 ventral anterior homeobox 1 [Source:HGNC Symbol;Acc:HGNC:12660] 90.68875429131269 -2.49911385994004 0.3984712983095221 -6.271753751254621 3.5700388802065e-10 1.28775703826846e-07 17.2086748132093 3.75812883505813 0.68697794711042 5.470523254590111 4.4870882365219696e-08 1.10067577347227e-06 both ENSG00000125538 22.237008696146198 4.16928130808884 0.8572099656130061 4.86378072507278 1.15164493219196e-06 0.00021222594015116002 112829751 112836816 2 IL1B interleukin 1 beta [Source:HGNC Symbol;Acc:HGNC:5992] 32.795447882773196 4.42740509859446 0.695204979394647 6.36848876204777 1.90899756714093e-10 7.181103419707861e-08 27.227488972634 4.10061886223397 0.530728199430223 7.72640094616472 1.10629809123351e-14 9.482555067715799e-13 both ENSG00000100985 67.027044493551 2.05677351589347 0.601153531822594 3.42137807900369 0.000623046529751106 0.025617805302801003 46008908 46016561 20 MMP9 matrix metallopeptidase 9 [Source:HGNC Symbol;Acc:HGNC:7176] 95.47982471441591 2.38105344636137 0.5011644260173239 4.7510424179210595 2.0237067070587397e-06 0.000315315059232371 72.9096075229704 4.15160647831911 0.458635032999883 9.05209192408152 1.40255156291741e-19 2.540535802628229e-17 both ENSG00000112333 Look at, how participate in cell cycle regulation, 1146.4954459826 -2.55782965063591 0.466872791503909 -5.47864364165779 4.2859857130920693e-08 1.25189746328771e-05 108166022 108188805 6 NR2E1 nuclear receptor subfamily 2 group E member 1 [Source:HGNC Symbol;Acc:HGNC:7973] 1293.77622502863 -1.1475710329820301 0.3897642666045471 -2.94426947595572 0.00323718003434007 0.0994649062593264 465.7806312236271 4.61516376363621 0.40071212447845295 11.5174048442958 1.0780925971608298e-30 6.7380787322552e-28 both ENSG00000173641 This gene encodes a small heat shock family B member 67.443611837479 3.36769370287841 0.838919527406252 4.01432270064156 5.96167368607794e-05 0.00454319677235686 16014028 16019594 1 HSPB7 heat shock protein family B (small) member 7 [Source:HGNC Symbol;Acc:HGNC:5249] 277.008981574488 5.17902858598066 1.23699465849104 4.1867833061610495 2.8293571275967705e-05 0.00304466556185598 234.13451946611 4.6385515328708475 0.9225150538508812 5.02815809184687 4.952135340023759e-07 9.367216910511529e-06 both ENSG00000198336 Myosins are a large family of motor proteins that share the common features of ATP hydrolysis (ATPase enzyme activity), actin binding and potential for kinetic energy transduction, Originally isolated from muscle cells, almost all eukaryotic cells are known to contain myosins 63.4773731501056 1.9332229161544 0.5991984758491601 3.2263481869087203 0.00125380726711889 0.0424689446457393 47200446 47223679 17 MYL4 myosin light chain 4 [Source:HGNC Symbol;Acc:HGNC:7585] 368.50214552482595 4.43012620968899 1.1775360236653 3.76220015409755 0.000168425172251046 0.0124384349091876 285.96471309180697 5.5165438183508595 1.07811200064886 5.11685596211782 3.1067068311316107e-07 6.19277109195671e-06 both ENSG00000118194 The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration, Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy, Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined, 43.47988412331039 1.70835125911111 0.5532089783476071 3.08807580132526 0.00201457077747987 0.0583136568292145 201359008 201377764 1 TNNT2 troponin T2, cardiac type [Source:HGNC Symbol;Acc:HGNC:11949] 513.956987434311 5.03322968797811 1.13681323017776 4.4274904217917 9.533580456805881e-06 0.00121863223586705 573.9327717693 6.01425433901132 1.05340038310811 5.709371702776459 1.13393998182646e-08 3.1498332828512895e-07 both ENSG00000197616 46.7225866903828 2.9615379035252403 1.0153434975524 2.9167842318036903 0.0035366033109534203 0.0860841396825253 23381982 23408273 14 MYH6 myosin heavy chain 6 [Source:HGNC Symbol;Acc:HGNC:7576] 1627.4583604718698 7.961859896325049 1.25219529178072 6.3583212208078805 2.0397059238841501e-10 7.56472343488979e-08 1268.8316901512899 9.704091791364519 1.08342666952824 8.95685150116347 3.34081165328053e-19 5.826997069675351e-17 both ENSG00000182718 alcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways, 4936.48562134158 1.6219276386652 0.451774717922443 3.59012484391312 0.000330519619939227 0.0158164186639429 60347134 60402883 15 ANXA2 annexin A2 [Source:HGNC Symbol;Acc:HGNC:537] 3523.34919922006 0.7653266374825971 0.24702692844471802 3.09815064414675 0.00194732414369132 0.0718164416690192 5015.23190369114 -0.4713259839343421 0.18664511706244602 -2.52525215420798 0.0115615300655842 0.0496771558246244 both ENSG00000101938 Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors, Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis, Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate, 690.384097954172 -1.74377852115039 0.47958065693894697 -3.63604848510891 0.000276852244848327 0.0137454389379331 110673856 110795819 X CHRDL1 chordin like 1 [Source:HGNC Symbol;Acc:HGNC:29861] 658.667521423946 -1.44753706965661 0.45293496822362794 -3.19590486760987 0.00139393063558681 0.0585730300396069 513.650456009057 -0.6587461895472929 0.2935671856911811 -2.2439367260899 0.0248364727347145 0.0900028082416882 both ENSG00000188933 104.889358256641 -1.6220276091173402 0.431802643373634 -3.756409632985549 0.000172368472193617 0.00994035720027342 16786489 16804455 17 USP32P1 ubiquitin specific peptidase 32 pseudogene 1 [Source:HGNC Symbol;Acc:HGNC:43570] 126.62287248793601 -1.18572102175594 0.32187551631944106 -3.68378755648872 0.00022979378111601093 0.0158401304825832 110.860055300429 -0.699976858019959 0.28101899992040696 -2.49085242712491 0.0127437038636241 0.0535767169652669 both ENSG00000114654 Calcium 314.365746256592 1.58583119909407 0.494798424239835 3.20500454610461 0.00135060347372976 0.04467120989361199 129001304 129040742 3 EFCC1 EF-hand and coiled-coil domain containing 1 [Source:HGNC Symbol;Acc:HGNC:25692] 301.698995327658 1.27629977634534 0.340200360080102 3.75161206779683 0.000175701183860098 0.0127103394873739 522.24927149659 -0.73871887872809 0.266459645622081 -2.7723480491894503 0.00556534956735265 0.0278871700385134 both ENSG00000279249 227.177103676849 1.5627247723118 0.43615851446906395 3.58292850069452 0.00033976362971274704 0.0161556528453899 49282021 49350504 16 novel transcript, antisense to CBLN1 220.66711115473598 1.3672018425261798 0.39329256228947707 3.47629722404939 0.000508388516469433 0.0286657096695356 390.30030115889195 -0.7935006723940059 0.31602608600409304 -2.51087080318974 0.0120433764905386 0.0512964956651511 both ENSG00000182674 Potassium Voltage-Gated Channel Subfamily B Member 2 55.029698196169214 -1.62283942952674 0.3666813161898061 -4.42574889386157 9.61082711122392e-06 0.00114368842623565 72537225 72938349 8 KCNB2 potassium voltage-gated channel subfamily B member 2 [Source:HGNC Symbol;Acc:HGNC:6232] 55.22988435181539 -1.15579307439604 0.286707985466118 -4.0312552596573195 5.54797486242272e-05 0.00516216516174258 52.1564356123627 -0.7996617138831741 0.25131721826568804 -3.1818819235767104 0.00146321459087753 0.0093000927386284 both ENSG00000286473 a lot in brain 425.403611406791 1.30189946891767 0.343788628870504 3.78691835502233 0.00015252718982189 0.00909944038802157 32126432 32132724 16 novel transcript 411.08239792325895 1.05457615219441 0.323855461421388 3.2563173323245 0.00112867529313359 0.0508038937073398 701.847054334675 -0.809123193026741 0.232914012152977 -3.47391376563173 0.000512925852205892 0.00388090178213789 both ENSG00000127084 Promotes the formation of filopodia, May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP, Plays a role in regulating the actin cytoskeleton and cell shape 304.790414441651 -1.9542320451573798 0.6850399023035451 -2.85272732082613 0.00433457979624683 0.0976844030033943 92947523 93036236 9 FGD3 FYVE, RhoGEF and PH domain containing 3 [Source:HGNC Symbol;Acc:HGNC:16027] 239.348203501223 -2.54753645974161 0.6127943855898249 -4.15724510479901 3.2210834956471196e-05 0.00333143833067103 123.25574993046001 -0.8551521053547059 0.2772322417258161 -3.0846055279546296 0.0020382228850786602 0.01229573427556 both ENSG00000169884 269.796940899743 2.2021161957255497 0.3108157883687769 7.08495603547905 1.3908845099908601e-12 1.5641191757102304e-09 48965340 48971735 12 WNT10B Wnt family member 10B [Source:HGNC Symbol;Acc:HGNC:12775] 172.10613758990002 1.17878493630437 0.32372798967544497 3.6412821068890797 0.000271283671628499 0.0178586041033041 316.044831345028 -0.8652713232672149 0.23770670602950197 -3.64007956578148 0.000272553806504266 0.00229854768285862 both ENSG00000198785 NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium, Mediated by glycine, May play a role in the development of dendritic spines, May play a role in PPP2CB-NMDAR mediated signaling mechanism 168.19019859643998 -2.04429688485525 0.7145705390728091 -2.86087485149867 0.004224737858011861 0.0962700903389511 101569352 101738647 9 GRIN3A glutamate ionotropic receptor NMDA type subunit 3A [Source:HGNC Symbol;Acc:HGNC:16767] 128.741738441598 -2.20041517063803 0.6248055165778521 -3.52176015136681 0.000428691812550493 0.0252604679473761 93.2720086586298 -0.9136155401434052 0.300363945764508 -3.04169509365714 0.00235250059824722 0.0138111581110404 both ENSG00000102924 Required for synapse integrity and synaptic plasticity, During cerebellar synapse formation, essential for the matching and maintenance of pre- and post-synaptic elements at parallel fiber-Purkinje cell synapses, the establishment of the proper pattern of climbing fiber-Purkinje cell innervation, and induction of long-term depression at parallel fiber-Purkinje cell synapses, Plays a role as a synaptic organizer that acts bidirectionally on both pre- and post-synaptic components, On the one hand induces accumulation of synaptic vesicles in the pre-synaptic part by binding with NRXN1 923.074003024939 1.8242598238054601 0.37614873920355296 4.84983633779579 1.2356338394501498e-06 0.000224118070024784 49277917 49281838 16 CBLN1 cerebellin 1 precursor [Source:HGNC Symbol;Acc:HGNC:1543] 843.480379516606 1.46115585106219 0.38561042965912296 3.78920210315327 0.00015113192436615 0.0113379083544429 1608.99299057478 -0.927208362920748 0.301220959827867 -3.07816681631518 0.00208278288943652 0.0125229976110063 both ENSG00000196104 227.377025428643 -1.97189336563835 0.624920633654649 -3.15543008094702 0.0016026167319850696 0.04992306498487 166733384 167234796 4 SPOCK3 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 [Source:HGNC Symbol;Acc:HGNC:13565] 165.968534600191 -2.5070320046391896 0.5221134331668991 -4.80169987091252 1.5732437098634398e-06 0.00025423851820717796 87.33195314916641 -0.954746755802073 0.221894044423149 -4.3027146505175295 1.6871808383132902e-05 0.00021116155673508001 both ENSG00000134207 calcium-dependent exocytosis of synaptic vesicles, 272.754492513828 -1.53065845534798 0.33789631808464504 -4.5299648839752695 5.89934909055255e-06 0.000764362606729751 114089291 114153880 1 SYT6 synaptotagmin 6 [Source:HGNC Symbol;Acc:HGNC:18638] 296.72693793920797 -0.9053164410310459 0.292124046123242 -3.0990822325153897 0.00194121132436464 0.07179210195669901 322.61632459711 -0.959673333709442 0.2156599182596 -4.449938317023 8.58949558553331e-06 0.00011758803243001202 both ENSG00000119946 ion (metal) transport 158.954772842912 -1.20609794854981 0.381654665757775 -3.1601813282043905 0.00157670978657614 0.0495276254327988 99329356 99394330 10 CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1 [Source:HGNC Symbol;Acc:HGNC:102] 145.51621226872498 -1.20405028831494 0.355683977433159 -3.3851687585258503 0.000711345063577191 0.0365129399885275 143.458668072308 -0.972679418968022 0.279993334161356 -3.4739377702737797 0.000512879967537637 0.00388090178213789 both ENSG00000172238 part of signalling way NOTHC https://www,ncbi,nlm,nih,gov/pmc/articles/PMC3346892/ 867.5040994298869 3.4969695764694797 0.457914983316126 7.63672232593295 2.22821333691874e-14 3.85498047389533e-11 93828753 93830964 4 ATOH1 atonal bHLH transcription factor 1 [Source:HGNC Symbol;Acc:HGNC:797] 417.574191814209 2.02535191467028 0.494352298866766 4.09698087641771 4.1857346635248e-05 0.0040973518646816 869.81046957946 -0.97369999842091 0.31091004298486197 -3.13177403043336 0.00173753551560339 0.0107079016984597 both ENSG00000132938 Binds microtubules, Together with MAPRE1 may target the microtubule depolymerase KIF2C to the plus-end of microtubules, May regulate the dynamics of microtubules at their growing distal tip 354.22702153922006 1.7060485933103502 0.2326393155636869 7.33344916002949 2.24303595719433e-13 3.1530076070786e-10 28820339 29505947 13 MTUS2 microtubule associated scaffold protein 2 [Source:HGNC Symbol;Acc:HGNC:20595] 252.014766489829 0.987592736262127 0.253614206291613 3.89407498382234 9.857415695083141e-05 0.00796213098413893 471.403596876299 -1.0453356460622099 0.22510057558185997 -4.64386038711867 3.41958686253198e-06 5.17074626390924e-05 both ENSG00000152977 It activates genes on chromosome 3, see if it somehow involves CNTN6 in the regulation. 7745.71977807427 1.51761496047683 0.309955544863007 4.89623426852254 9.76905971505507e-07 0.000187273245717502 147393422 147510293 3 ZIC1 Zic family member 1 [Source:HGNC Symbol;Acc:HGNC:12872] 6423.89909859573 0.9039304557918141 0.305791211664342 2.9560380459332203 0.00311618649013523 0.0979181654632946 12137.288995786 -1.0464041698517 0.240269404126654 -4.35512866756896 1.32988779184541e-05 0.00017152465071093 both ENSG00000002933 425.2117304834021 2.51396505428174 0.509597726124815 4.93323444238839 8.08789793886945e-07 0.000159565712757116 150800403 150805118 7 TMEM176A transmembrane protein 176A [Source:HGNC Symbol;Acc:HGNC:24930] 241.94986231469397 1.25205417458805 0.4151925781770901 3.01559864120216 0.00256472501324552 0.0858082727983899 479.606083996458 -1.08012167204951 0.3733126921205921 -2.8933430200669403 0.0038116477185968 0.0206257993430563 both ENSG00000135406 axon elongation, белок промежуточный филамент 724.2897198509738 2.35106663250714 0.36718225849420794 6.40299627261056 1.5235691398576995e-10 1.10537398466257e-07 49293252 49298686 12 PRPH peripherin [Source:HGNC Symbol;Acc:HGNC:9461] 512.385317031127 1.47251888489469 0.45509624837130397 3.2356207948637903 0.00121378515816594 0.053357914498874004 1079.32023853079 -1.11420680582459 0.4582301913112801 -2.4315438549261903 0.0150346281219076 0.060926495158345 both ENSG00000161509 Glutamate Ionotropic Receptor NMDA Type Subunit 2C 81.5400968864238 2.1959020476936 0.377304207346609 5.81997763326381 5.88555028230338e-09 2.4270550743645197e-06 74842023 74861504 17 GRIN2C glutamate ionotropic receptor NMDA type subunit 2C [Source:HGNC Symbol;Acc:HGNC:4587] 52.27302700869701 1.03143814770473 0.261043270191165 3.95121524086559 7.77553523919907e-05 0.00669102594505196 94.12312110383341 -1.1207135135628998 0.252940935267857 -4.43073206942996 9.39137173154751e-06 0.00012662523682985401 both ENSG00000174963 " a transcription factor, in development, especially in the cerebellum" 1681.77555456151 1.9124140629751205 0.36232072078016603 5.27823542318314 1.30433821685536e-07 3.1514590367389696e-05 147386046 147406809 3 ZIC4 Zic family member 4 [Source:HGNC Symbol;Acc:HGNC:20393] 1273.59785710752 1.21199239853882 0.398557411489284 3.0409480882816498 0.00235834487418782 0.0812826403496253 2746.50936290558 -1.16717062585954 0.291457890956557 -4.00459435848149 6.21239905882285e-05 0.000649832537533771 both ENSG00000163132 3112.84798448438 2.65050839855743 0.29347691181587104 9.031403465974767 1.69483978691831e-19 8.93866615920107e-16 4859665 4863936 4 MSX1 msh homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7391] 1716.45040278769 1.37862310848169 0.244002894807494 5.6500276751608 1.60422007664211e-08 4.35487866578763e-06 3699.58470241334 -1.20162587809604 0.278409218821301 -4.3160419873428 1.58851776728621e-05 0.000200908655221696 both ENSG00000121966 "It is expressed in neural stem cells !!! and very good for glutamatergic ones! " https://www,karger,com/Article/Fulltext/339091 2197.28831280443 1.32233375461945 0.24541278842050104 5.38820231468011 7.11659162852989e-08 2.02606661161096e-05 136114349 136118149 2 CXCR4 C-X-C motif chemokine receptor 4 [Source:HGNC Symbol;Acc:HGNC:2561] 1769.6775136081894 0.7005350568085129 0.2364516437277769 2.96269903547394 0.00304954580749108 0.0966596900618108 3473.3051520740505 -1.2206486183133898 0.19602588317030809 -6.22697675721161 4.75521632676165e-10 1.81728012487706e-08 both ENSG00000174279 Homeobox Even-Skipped Homolog Protein 2 145.904886560947 3.44752171962711 0.49286308898128495 6.9948872145262815 2.6547240297968197e-12 2.71397264337092e-09 176077472 176083913 2 EVX2 even-skipped homeobox 2 [Source:HGNC Symbol;Acc:HGNC:3507] 78.5734648182353 2.15240555577334 0.6328662858243511 3.4010431650181605 0.0006712922696059017 0.0354049501160759 187.940129924621 -1.24227709355269 0.454812385187236 -2.7314055949493903 0.0063064805888808 0.0308385358869477 both ENSG00000105894 2530.76675624492 0.9247488241829872 0.27517747317158503 3.3605542398682005 0.000777862556248987 0.0304962468890612 137227341 137343774 7 PTN pleiotrophin [Source:HGNC Symbol;Acc:HGNC:9630] 2662.41201892547 0.85636544011378 0.27610553793057896 3.1015873369736497 0.00192486082035652 0.0712875318166354 5522.6022955163 -1.2773032784715301 0.23729710395042106 -5.3827175182820906 7.3369632278053e-08 1.70627051809426e-06 both ENSG00000143171 Receptor for retinoic acid, контроль транскрипционной программы нейрогенеза https://pubmed,ncbi,nlm,nih,gov/28778663/ 220.773918998417 2.4491229345175096 0.294466807959689 8.31714430392705 9.010801859649541e-17 2.2517993847264201e-13 165400922 165445355 1 RXRG retinoid X receptor gamma [Source:HGNC Symbol;Acc:HGNC:10479] 146.18662203828399 1.4581794132488501 0.45208444991548097 3.2254580167963396 0.00125771280739477 0.0548312808680781 330.613834128942 -1.27950811321704 0.428654283096626 -2.9849418603117504 0.00283632227651887 0.0161729643970694 both ENSG00000106038 199.51210920091202 2.9542474790857405 0.421744749441042 7.0048233748046504 2.47297608949841e-12 2.6485573918527997e-09 27242700 27250493 7 EVX1 even-skipped homeobox 1 [Source:HGNC Symbol;Acc:HGNC:3506] 111.36961941212499 1.6913528107222 0.301272199951748 5.61403545031066 1.9766169171599e-08 5.204827666265451e-06 260.67972428657004 -1.28046896997306 0.427583133771289 -2.9946666948233096 0.00274744884205408 0.0157657737684817 both ENSG00000101638 The protein encoded by this gene is a type II membrane protein that may be present in the Golgi apparatus, The encoded protein, which is a member of glycosyltransferase family 29, may be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b, and GT3 from GD1a, GT1b, GM1b, and GD3, respectively, https://pubmed,ncbi,nlm,nih,gov/22189683/ 150.933677518489 -2.70873074069408 0.8639782089533671 -3.13518409680201 0.00171746294107202 0.052400443303325994 46667821 46759257 18 ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 [Source:HGNC Symbol;Acc:HGNC:17827] 129.10993325521602 -3.00029729883969 0.7547502739694159 -3.9752185621084895 7.03146514243432e-05 0.00625515338278988 71.23773515863141 -1.29753061439802 0.404869104119009 -3.2048150901053103 0.00135149274050313 0.00869127164310693 both ENSG00000128683 403.387874992973 -2.51233255163005 0.6370664070602919 -3.94359602670477 8.026882879185491e-05 0.00568336148916043 170813213 170861151 2 GAD1 glutamate decarboxylase 1 [Source:HGNC Symbol;Acc:HGNC:4092] 345.893570902853 -2.55981731394742 0.462024450468832 -5.54043689971361 3.01717944025995e-08 7.7134338855267e-06 214.698341402727 -1.33594637450222 0.3883728192034889 -3.43985549051064 0.00058202486478627 0.00431129529471311 both ENSG00000100505 362.902641902828 -1.17123846807805 0.368531612854248 -3.17812211280032 0.00148232305732755 0.047695175797359005 50975262 51096061 14 TRIM9 tripartite motif containing 9 [Source:HGNC Symbol;Acc:HGNC:16288] 302.926966794286 -1.39089292291386 0.308613381441162 -4.50691060905615 6.57783283881598e-06 0.0009099717822922779 346.876318834848 -1.3484724445782 0.18443958634882 -7.311187751353519 2.64791238298334e-13 1.8560133525584106e-11 both ENSG00000198822 G-protein coupled receptor for glutamate, Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, Signaling inhibits adenylate cyclase activity, 178.60555086678505 -1.19886977562762 0.378479584293343 -3.16759430463342 0.00153705849447801 0.0488967222055232 86643909 86864879 7 GRM3 glutamate metabotropic receptor 3 [Source:HGNC Symbol;Acc:HGNC:4595] 149.870479867201 -1.51328410828919 0.389439040983117 -3.88580483474125 0.00010199142181911 0.00816303379738846 169.358920514349 -1.41424292894988 0.324696636399128 -4.35558232026598 1.3271362809729305e-05 0.000171390824060215 both ENSG00000185739 transfer Ca2+ 193.09622082043398 1.99309547770075 0.330789100758381 6.025275540008099 1.68821762264462e-09 8.830163383930279e-07 4189374 4242080 16 SRL sarcalumenin [Source:HGNC Symbol;Acc:HGNC:11295] 122.85603936602502 0.926688104605687 0.25194042998122196 3.6782032350852 0.00023488277223625 0.0160647614507141 290.163486750946 -1.50254921224107 0.200529926945377 -7.492892632681 6.73720126451193e-14 5.12179151884385e-12 both ENSG00000108001 "Breaking the transition multi-polar to bipolar!!! The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies" https://www,sciencedirect,com/science/article/pii/S0006291X17321988?via%3Dihub#fig1 1216.9138154921 1.56355709753338 0.16753731086720405 9.33259039100077 1.03314448221926e-20 7.74548418319779e-17 129835233 129973053 10 EBF3 EBF transcription factor 3 [Source:HGNC Symbol;Acc:HGNC:19087] 958.591990079202 0.889841263858822 0.248170263253488 3.5856079297861405 0.00033629388196149704 0.0208359776466121 2225.78774384892 -1.51707163561901 0.248933456189555 -6.09428583381659 1.0992709109441197e-09 3.83021223325476e-08 both ENSG00000106153 Transcription factor, Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen) 133.61511595145902 -3.2052402315716098 0.6401939825995949 -5.0066703510025095 5.5379650603617e-07 0.000116405955301491 56101573 56106476 7 CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21645] 686.91216826296 1.9641117185424501 0.502117547625424 3.9116571962700295 9.16649620823043e-05 0.0075903200677711795 1882.81603106178 -1.5457126067301499 0.255758401844269 -6.0436435150675285 1.5067222715340802e-09 5.07313896139419e-08 both ENSG00000166407 May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors, 164.641869698156 -2.13400274119627 0.562385804439891 -3.7945529996469904 0.000147909685815596 0.00891859716803907 8224309 8268716 11 LMO1 LIM domain only 1 [Source:HGNC Symbol;Acc:HGNC:6641] 143.574815974059 -2.03107357786755 0.4735057909276501 -4.2894376727441 1.79126071718554e-05 0.00205971516178732 138.003589028724 -1.59634933131558 0.2735658428685089 -5.8353386321072005 5.36814285432056e-09 1.59924811945995e-07 both ENSG00000173917 2437.14619895933 2.1447363280648797 0.31138077443464 6.887825145784872 5.6651781904316925e-12 5.539805333956479e-09 48540894 48545109 17 HOXB2 homeobox B2 [Source:HGNC Symbol;Acc:HGNC:5113] 1706.11714593958 1.25913178720046 0.24769314454378602 5.08343413992983 3.70671143654025e-07 7.33873124413368e-05 4459.2849109669205 -1.6170626335779699 0.21774526910893305 -7.42639617473844 1.11596417293256e-13 8.16559150926263e-12 both ENSG00000168081 Ligand of the opioid receptor-like receptor OPRL1, может участвовать в дифференцировке нейральной 34.8062193561509 -2.90279259162448 0.7837452427001059 -3.70374508638034 0.000212439739202021 0.0115132100587775 28316986 28343355 8 PNOC prepronociceptin [Source:HGNC Symbol;Acc:HGNC:9163] 30.2564994324297 -2.1907449496931 0.651163444614702 -3.3643549370149 0.0007672280479927468 0.0387766774659213 28.228199873828697 -1.7072143807172298 0.5211342228725979 -3.2759590634956197 0.00105303823082063 0.0070610520618281 both ENSG00000037965 115.124894927605 3.21860031177845 0.70213387348059 4.5840265415814905 4.56106303799435e-06 0.000629342753297736 54008985 54012769 12 HOXC8 homeobox C8 [Source:HGNC Symbol;Acc:HGNC:5129] 70.3013744250145 2.12840978331339 0.580770732361928 3.6648020719938796 0.000247529935526493 0.0166798266398144 217.35912442384 -1.74852535498858 0.458806613903786 -3.8110290959215702 0.000138389475681424 0.0012998385317604 both ENSG00000111432 WNT 1852.9107680488 1.9413340329278896 0.339696891256774 5.71490079213135 1.09768044061749e-08 3.9187191730044286e-06 130162459 130165740 12 FZD10 frizzled class receptor 10 [Source:HGNC Symbol;Acc:HGNC:4039] 1268.2639646299301 1.01174161366521 0.315647914425249 3.20528527966819 0.00134928676166568 0.0573055145293238 3475.3895535968395 -1.76853934179522 0.261195421370375 -6.77094312188357 1.27945571383218e-11 6.48372827955499e-10 both ENSG00000235934 62.062025102686604 -2.49781546237617 0.667782474081698 -3.74046273947372 0.000183681775662335 0.0104060121320443 170814686 170818037 2 novel transcript 52.18672060810179 -2.7540549401616 0.5737128616635029 -4.8004064823928 1.58343904701417e-06 0.00025423851820717796 37.5813253544244 -1.81415752158311 0.5549804900253 -3.26886720198111 0.00107978967011063 0.007214630312543171 both ENSG00000286478 lnc-RNA 31.4264672219311 3.3183320402032597 0.5755895160945339 5.76510160004071 8.160866340056309e-09 3.06792774703733e-06 27617474 27627496 7 novel transcript, antisense to HIBADH 15.9963221239134 1.9306619819511104 0.600816367927691 3.2133977784431296 0.00131174481693181 0.0563472504395571 50.4686571853455 -1.81476849818834 0.30585406983264896 -5.933445643477322 2.9664223884072e-09 9.34796971136722e-08 both ENSG00000154646 28.794882691107002 3.6087658825277997 0.620214820858113 5.81857408298435 5.93517536303625e-09 2.4270550743645197e-06 18269116 18485879 21 TMPRSS15 transmembrane serine protease 15 [Source:HGNC Symbol;Acc:HGNC:9490] 21.110725627577104 3.0771364863520096 0.9835097389829208 3.1287300617217797 0.00175563512845133 0.0679895022375833 61.7296321002819 -1.8193004753187296 0.696291782532582 -2.6128420885587595 0.008979277968283591 0.0408272717563667 both ENSG00000078399 116.359769697237 3.0784274427820804 0.571953216750178 5.382306371618331 7.353746234824232e-08 2.0376385454545397e-05 27162438 27175180 7 HOXA9 homeobox A9 [Source:HGNC Symbol;Acc:HGNC:5109] 121.806802367974 2.91307722130601 0.4911806909124529 5.930764940890629 3.01526616842218e-09 9.265049532957541e-07 383.653791814653 -1.8949003548610401 0.47616408802053795 -3.9795112704495 6.9057086420225e-05 0.000711928725981701 both ENSG00000283761 112.962255070354 -1.1660025106097198 0.37178960547701395 -3.13618910650746 0.0017115879986188 0.0523034316262708 99970011 100083321 1 novel protein 96.3521071239125 -2.6056291352280296 0.4858444993890779 -5.36309279719017 8.18089502197617e-08 1.85706316998859e-05 84.79818187953221 -2.00623207889371 0.416901983671474 -4.8122392252147685 1.4924854956657301e-06 2.50137233910457e-05 both ENSG00000105996 735.4081722983127 2.195563398578 0.30051139304826596 7.3060903824879695 2.7502721357187895e-13 3.6386100355559604e-10 27100354 27102686 7 HOXA2 homeobox A2 [Source:HGNC Symbol;Acc:HGNC:5103] 437.339872559062 1.01730739896318 0.325895156667594 3.12157875976296 0.0017988412416103398 0.0688610253114607 1373.66731343836 -2.01311861233176 0.254097288291907 -7.922629264815639 2.32540136342645e-15 2.2146679651680498e-13 both ENSG00000115665 sodium ion- and chloride ion-dependent high-affinity transporter в нейронах 81.13206119311171 3.33731551304258 0.6351992454477801 5.25396643172955 1.4885802319198401e-07 3.48746437459471e-05 107986523 108013994 2 SLC5A7 solute carrier family 5 member 7 [Source:HGNC Symbol;Acc:HGNC:14025] 37.86826555767711 1.84734478093469 0.598773311691265 3.0852156314662302 0.00203404627149411 0.0738765605806662 136.894819212503 -2.1040351282646497 0.4171418113759261 -5.04393247304692 4.56060304532053e-07 8.70344092618421e-06 both ENSG00000233101 HOXB Cluster Antisense RNA 3 60.748271940034996 3.1915862484257103 0.6410207950611689 4.9789121866493495 6.39426441977133e-07 0.000130985878592625 48549630 48606414 17 HOXB-AS3 HOXB cluster antisense RNA 3 [Source:HGNC Symbol;Acc:HGNC:40283] 48.8637646394167 2.54648990608698 0.702207487107268 3.6264066573502403 0.00028739263947194504 0.0184576170306714 247.852500765494 -2.5787531560906203 0.761300070950277 -3.3873018727973396 0.000705836774209529 0.00507309612512838 both ENSG00000122592 96.98996230918979 4.20013279437717 0.540001475940409 7.77800243427606 7.367865247448805e-15 1.50646052073065e-11 27153716 27157936 7 HOXA7 homeobox A7 [Source:HGNC Symbol;Acc:HGNC:5108] 45.543384601293 2.72214714309846 0.49336751977473403 5.51748348643089 3.4388838657126896e-08 8.70698941845639e-06 250.341840045635 -2.58171996766107 0.3686764159541209 -7.002671871428701 2.51126519827406e-12 1.47721482251415e-10 both ENSG00000243566 UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins, The other major conserved integral membrane proteins of urothelial plaques are UPK1A 78.696560503808 2.51119423288692 0.8766443282170991 2.864553105584029 0.00417598126023691 0.0955462813061935 76510525 76516522 7 UPK3B uroplakin 3B [Source:HGNC Symbol;Acc:HGNC:21444] 15.676614098594401 -1.9529718809657601 0.513128290922174 -3.80601092458956 0.000141226147167339 0.0106861118023287 26.0895620819493 -2.59429302649254 0.6134943300810479 -4.22871557125852 2.35029251203012e-05 0.000280241555488488 both ENSG00000244694 Could act as a repressor of canonical hedgehog signaling by antagonizing the effects of SMO, as suggested by down-regulation of hedgehog target genes, including GLI1, PTCH1, and PTCH2 in PTCHD4-expressing cells, 318.292448791141 0.944254588908668 0.30241827674296995 3.1223463048538 0.0017941575759527699 0.0539470562042162 47856673 48111197 6 PTCHD4 patched domain containing 4 [Source:HGNC Symbol;Acc:HGNC:21345] 128.973282587027 -1.028588708705 0.24574585965568901 -4.18557899671695 2.844401216073869e-05 0.00304466556185598 397.783576594033 -2.64351692940789 0.251571155323761 -10.508028736465501 7.93344597830749e-26 2.9975123941182e-23 both ENSG00000101438 The protein encoded by this gene is an integral membrane protein involved in gamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles, The encoded protein is a member of amino acid/polyamine transporter family II, 199.778847795232 -3.23806549781729 0.865300929168694 -3.74212645412058 0.000182469649911899 0.0103634467074963 38724486 38729372 20 SLC32A1 solute carrier family 32 member 1 [Source:HGNC Symbol;Acc:HGNC:11018] 157.81870832457702 -3.4914179396970804 0.7835125854493159 -4.456109582075031 8.346038232251989e-06 0.0010988393936583 122.965851165548 -2.69997509170497 0.41205085129911995 -6.552528852185231 5.6570784133159404e-11 2.5406040778365e-09 both ENSG00000273079 53.955419037389 -1.7312402104432199 0.41405090915800197 -4.18122547771675 2.8994216415003303e-05 0.0025980435115133 13437942 13982002 12 GRIN2B glutamate ionotropic receptor NMDA type subunit 2B [Source:HGNC Symbol;Acc:HGNC:4586] 46.7735450169345 -2.0825418417528896 0.326400746512505 -6.3803219324840095 1.76716096961514e-10 6.84307097822143e-08 85.25470740392 -2.7347226776224103 0.34503787236359 -7.925862337629559 2.2656848125140998e-15 2.17158288739371e-13 both ENSG00000197757 260.26537777198297 3.99976176386612 0.552555101442721 7.23866588766034 4.5311974755830197e-13 5.66173124574098e-10 53990624 54030823 12 HOXC6 homeobox C6 [Source:HGNC Symbol;Acc:HGNC:5128] 116.830937309741 2.45661221308307 0.35249430228572 6.96922530989401 3.18690963845936e-12 1.64544518823356e-09 658.953474867722 -2.7396968488959597 0.321627294774902 -8.51823490544669 1.6200335724468302e-17 2.2500466283983802e-15 both ENSG00000175879 35.8404184126526 4.20840456256562 0.7908408722865219 5.3214302776209 1.0295456947223901e-07 2.63130820681833e-05 176129694 176132695 2 HOXD8 homeobox D8 [Source:HGNC Symbol;Acc:HGNC:5139] 21.1283329856889 3.22909251095524 0.6438341967372591 5.01541006569583 5.29204744284336e-07 0.00010171546953646099 118.958151242598 -2.8496064269182004 0.353053446529818 -8.07131740230025 6.95436678951624e-16 7.372120271571989e-14 both ENSG00000170689 224.593658574944 3.4997698142423497 0.566195874297491 6.18119978105581 6.36162476453688e-10 4.0879800736914e-07 48621156 48626358 17 HOXB9 homeobox B9 [Source:HGNC Symbol;Acc:HGNC:5120] 325.431205120793 3.7510028821353503 0.22283464945009496 16.833122188995098 1.3954558568709793e-63 1.22483812077089e-59 2143.9096607974498 -2.91354563423002 0.49987750778400303 -5.82851916491701 5.59213756880339e-09 1.65284854250347e-07 both ENSG00000180806 43.005483344443 3.8217670189080213 0.8109663136484679 4.712608840328049 2.4456537741878503e-06 0.000392894278823279 53994895 54003337 12 HOXC9 homeobox C9 [Source:HGNC Symbol;Acc:HGNC:5130] 17.996974774284602 2.2375075257024304 0.5826981870910629 3.8399081639029697 0.000123080342775407 0.00944883844303794 125.40141410285 -2.98719956206208 0.46872067222645797 -6.3730911373562 1.8525571924571801e-10 7.623692150029542e-09 both ENSG00000273433 7.534529538523329 6.34429905724054 1.6540738637573302 3.83555970277475 0.00012527866817784098 0.007870509849128009 27128969 27152561 7 novel transcript 7.24169422547269 5.94630727163031 1.6609468164919698 3.58007084428466 0.00034350106584569 0.0211828338778658 56.16941428161741 -3.10537439658945 0.678288142859593 -4.578252515955112 4.6887647025816295e-06 6.85826138846655e-05 both ENSG00000180818 Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis 23.3837032831082 4.240736669846109 0.9612988563620648 4.41146542698983 1.0267335028447e-05 0.00120901901636022 53985065 53990279 12 HOXC10 homeobox C10 [Source:HGNC Symbol;Acc:HGNC:5122] 11.373847908158199 2.81844757278508 0.805390689738271 3.4994787110104197 0.00046616882830198206 0.0268603010653124 74.49730635288479 -3.1202010354400294 0.579921564830859 -5.380384563471218 7.432688807463388e-08 1.7205298165424499e-06 both ENSG00000154478 This gene encodes a G protein-couple receptor protein, G-protein-coupled receptors are a large family of membrane proteins that are involved in cellular responses to environmental stimuli, neurotransmitters, and hormones, The encoded protein may play a role in neurodegenerative diseases, 19.6539070328443 -3.44600528995819 0.9677871925587708 -3.56070561426543 0.000369859560912074 0.017402743482161996 123666355 123697399 10 GPR26 G protein-coupled receptor 26 [Source:HGNC Symbol;Acc:HGNC:4481] 15.505488113785699 -3.65037290757407 0.828096598025211 -4.4081486583560805 1.04257977847503e-05 0.00130729574889545 16.940481216584597 -3.40153421057735 0.797124322331363 -4.26725683219504 1.97891288529861e-05 0.000242414808325677 both